Function and Biology Details
Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-225519 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
DNA polymerase I, thermostable
Molecule details ›
Chain: T
Length: 832 amino acids
Theoretical weight: 94.05 KDa
Source organism: Thermus aquaticus
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 832 amino acids
Theoretical weight: 94.05 KDa
Source organism: Thermus aquaticus
Expression system: Escherichia coli
UniProt:
- Canonical:
P19821 (Residues: 1-832; Coverage: 100%)
Sequence domains:
- 5'-3' exonuclease, N-terminal resolvase-like domain
- 5'-3' exonuclease, C-terminal SAM fold
- Taq polymerase, exonuclease
- DNA polymerase family A
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SIEMENS
Spacegroup:
P1
Expression systems:
- Escherichia coli
- Mus musculus
