› 1bv8

Solution NMR

RECEPTOR DOMAIN FROM ALPHA-2-MACROGLOBULIN

Released:
DOI: 10.2210/pdb1bv8/pdb
PDB entry 1bv8 coloured by chain, front view.
PDB entry 1bv8 coloured by chain, side view.
PDB entry 1bv8 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
NMR solution structure of complement-like repeat CR8 from the low density lipoprotein receptor-related protein.
Huang W, Dolmer K, Gettins PG
J Biol Chem 274 14130-6 (1999)
PMID: 10318830

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133819 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-2-macroglobulin Chain: A
Molecule details ›
Chain: A
Length: 138 amino acids
Theoretical weight: 15.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01023 (Residues: 1337-1474; Coverage: 10%)
Gene names: A2M, CPAMD5, FWP007
Sequence domains: A-macroglobulin receptor binding domain
Structure domains: Alpha-macroglobulin, receptor-binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry
Expression system: Escherichia coli

Quick links

Citations

10 review citations

LRP: a multifunctional scavenger and signaling receptor.
Herz et al. (2001)
9 more

4 mentions without citation

The structural network of Interleukin-10 and its implications in inflammation and cancer.
Acuner-Ozbabacan et al. (2014)
3 more