› 1bw5

Solution NMR

THE NMR SOLUTION STRUCTURE OF THE HOMEODOMAIN OF THE RAT INSULIN GENE ENHANCER PROTEIN ISL-1, 50 STRUCTURES

Released:
DOI: 10.2210/pdb1bw5/pdb
PDB entry 1bw5 coloured by chain, ensemble of 50 models, front view.
PDB entry 1bw5 coloured by chain, ensemble of 50 models, side view.
PDB entry 1bw5 coloured by chain, ensemble of 50 models, top view.
Source organism: Rattus norvegicus
Primary publication:
The solution structure of the homeodomain of the rat insulin-gene enhancer protein isl-1. Comparison with other homeodomains.
Ippel H, Larsson G, Behravan G, Zdunek J, Lundqvist M, Schleucher J, Lycksell PO, Wijmenga S
J Mol Biol 288 689-703 (1999)
PMID: 10329173

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156198 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Insulin gene enhancer protein ISL-2 Chain: A
Molecule details ›
Chain: A
Length: 66 amino acids
Theoretical weight: 7.89 KDa
Source organism: Rattus norvegicus
UniProt:
  • Canonical: P50480 (Residues: 191-255; Coverage: 18%)
Gene names: Isl-2, Isl2
Sequence domains: Homeodomain
Structure domains: Homeodomain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing

Quick links

Citations

11 citation in other articles

Relationship between ion pair geometries and electrostatic strengths in proteins.
Kumar et al. (2002)
10 more

3 mentions without citation

Chemical shift prediction for protein structure calculation and quality assessment using an optimally parameterized force field.
Nielsen et al. (2012)
2 more