› 1bxc

X-ray diffraction
2.3Å resolution

XYLOSE ISOMERASE FROM THERMUS CALDOPHILUS

Released:
DOI: 10.2210/pdb1bxc/pdb
PDB entry 1bxc coloured by chain, front view.
PDB entry 1bxc coloured by chain, side view.
PDB entry 1bxc coloured by chain, top view.
Source organism: Thermus caldophilus
Primary publication:
Crystal structures of thermostable xylose isomerases from Thermus caldophilus and Thermus thermophilus: possible structural determinants of thermostability.
Chang C, Park BC, Lee DS, Suh SW
J Mol Biol 288 623-34 (1999)
PMID: 10329168

Function and Biology Details

Reaction catalysed: 
Alpha-D-xylopyranose = alpha-D-xylufuranose
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157520 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Xylose isomerase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 387 amino acids
Theoretical weight: 43.98 KDa
Source organism: Thermus caldophilus
Expression system: Escherichia coli
UniProt:
  • Canonical: P56681 (Residues: 1-387; Coverage: 100%)
Gene name: xylA
Sequence domains: Xylose isomerase-like TIM barrel
Structure domains: Divalent-metal-dependent TIM barrel enzymes

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6A
Spacegroup: P212121
Unit cell:
a: 84.35Å b: 123.6Å c: 140.24Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.178 0.178 0.264
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Tagatose: properties, applications, and biotechnological processes.
Oh DK. (2007)
1 more