› 1bxh

X-ray diffraction
2.75Å resolution

CONCANAVALIN A COMPLEXED TO METHYL ALPHA1-2 MANNOBIOSIDE

Released:
DOI: 10.2210/pdb1bxh/pdb
PDB entry 1bxh coloured by chain, front view.
PDB entry 1bxh coloured by chain, side view.
PDB entry 1bxh coloured by chain, top view.
Source organism: Canavalia ensiformis
Primary publication:
Man alpha1-2 Man alpha-OMe-concanavalin A complex reveals a balance of forces involved in carbohydrate recognition.
Moothoo DN, Canan B, Field RA, Naismith JH
Glycobiology 9 539-45 (1999)
PMID: 10336986

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136271 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Concanavalin-A, 2nd part Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 237 amino acids
Theoretical weight: 25.62 KDa
Source organism: Canavalia ensiformis
UniProt:
  • Canonical: P02866 (Residues: 28-148; Coverage: 46%)
Sequence domains: Legume lectin domain
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: MMA, AMG
Ligand MMA 1 x MMA
Ligand AMG 1 x AMG
Carbohydrate polymer : NEW Components: AMG
Ligand AMG 2 x AMG
3 bound ligands:
Ligand MN 4 x MN
Ligand CA 4 x CA
Ligand MMA 2 x MMA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: OTHER
Spacegroup: P212121
Unit cell:
a: 119.7Å b: 119.7Å c: 68.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.196 0.238

Quick links

Citations

3 review citations

LG/LNS domains: multiple functions -- one business end?
Rudenko et al. (2001)
2 more

4 mentions without citation

Overview of the Structure⁻Function Relationships of Mannose-Specific Lectins from Plants, Algae and Fungi.
Barre et al. (2019)
3 more