› 1c0c

X-ray diffraction
2Å resolution

BOVINE PANCREATIC RIBONUCLEASE A DESICCATED FOR 4.0 DAYS

Released:
DOI: 10.2210/pdb1c0c/pdb
PDB entry 1c0c coloured by chain, front view.
PDB entry 1c0c coloured by chain, side view.
PDB entry 1c0c coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
X-ray crystal structures of a severely desiccated protein.
Bell JA
Protein Sci 8 2033-40 (1999)
PMID: 10548049

Function and Biology Details

Reaction catalysed: 
(1a) an (RNA) containing cytidine = an (RNA)-3'-cytidine-2',3'-cyclophosphate + a 5'-hydroxy-ribonucleotide-3'-(RNA)
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158390 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribonuclease pancreatic Chain: A
Molecule details ›
Chain: A
Length: 128 amino acids
Theoretical weight: 14.06 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P61823 (Residues: 23-150; Coverage: 100%)
Gene names: RNASE1, RNS1
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain

Ligands and Environments

1 bound ligand:
Ligand SO4 3 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P212121
Unit cell:
a: 35.7Å b: 39.7Å c: 50.8Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.185 0.268

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Citations

2 review citations

Thermodynamic and dynamic factors involved in the stability of native protein structure in amorphous solids in relation to levels of hydration.
Hill et al. (2005)
1 more

2 mentions without citation

NMR of hydrogen bonding in cold-shock protein A and an analysis of the influence of crystallographic resolution on comparisons of hydrogen bond lengths.
Alexandrescu et al. (2001)
1 more