Function and Biology Details
Reaction catalysed:
Specific cleavage of Arg-|-Val bond in plasminogen to form plasmin.
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Urokinase-type plasminogen activator chain B (preferred)
PDBe Complex ID:
PDB-CPX-133250 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Urokinase-type plasminogen activator short chain A
Molecule details ›
Chain: A
Length: 23 amino acids
Theoretical weight: 2.71 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
Length: 23 amino acids
Theoretical weight: 2.71 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
- Canonical:
P00749 (Residues: 156-178; Coverage: 6%)
Urokinase-type plasminogen activator chain B
Molecule details ›
Chain: B
Length: 253 amino acids
Theoretical weight: 28.44 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
Length: 253 amino acids
Theoretical weight: 28.44 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
- Canonical: P00749 (Residues: 179-431; Coverage: 62%)
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
