Function and Biology Details
Reaction catalysed:
Endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -(Man(GlcNAc)(2))Asn- structure. One N-acetyl-D-glucosamine residue remains attached to the protein, the rest of the oligosaccharide is released intact.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Endo-beta-N-acetylglucosaminidase H (preferred)
PDBe Complex ID:
PDB-CPX-137384 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Endo-beta-N-acetylglucosaminidase H
Molecule details ›
Chain: A
Length: 265 amino acids
Theoretical weight: 28.47 KDa
Source organism: Streptomyces plicatus
Expression system: Escherichia coli
UniProt:
Structure domains: Glycosidases
Length: 265 amino acids
Theoretical weight: 28.47 KDa
Source organism: Streptomyces plicatus
Expression system: Escherichia coli
UniProt:
- Canonical:
P04067 (Residues: 48-312; Coverage: 98%)
Structure domains: Glycosidases
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
RIGAKU RU200
Spacegroup:
P21
Expression system: Escherichia coli
