› › Structure analysis

STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 IN COMPLEX WITH A PEPTIDE FROM TNF-R2

X-ray diffraction
2.3Å resolution
PDB entry 1ca9 coloured by chain, front view.
PDB entry 1ca9 coloured by chain, side view.
PDB entry 1ca9 coloured by chain, top view.
Source organism: Homo sapiens
Assemblies composition:
hetero pentamer (preferred)
homo trimer
hetero octamer
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: TNF receptor-associated factor 2 and Tumor necrosis factor-binding protein 2
hide full assembly name
Multimeric state: hetero pentamer
Accessible surface area: 28238.11 Å2
Buried surface area: 6466.19 Å2
Dissociation area: 540.88 Å2
Dissociation energy (ΔGdiss): 3.06 kcal/mol
Dissociation entropy (TΔSdiss): 7.53 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-148932
Assembly 2
Download    3D Visualisation
Assembly Name: TNF receptor-associated factor 2
hide full assembly name
Multimeric state: homo trimer
Accessible surface area: 26830.82 Å2
Buried surface area: 4384.77 Å2
Dissociation area: 2,192.39 Å2
Dissociation energy (ΔGdiss): 17.62 kcal/mol
Dissociation entropy (TΔSdiss): 25.98 kcal/mol
Symmetry number: 3
PDBe Complex ID: PDB-CPX-171450
Assembly 3
Download    3D Visualisation
Assembly Name: TNF receptor-associated factor 2 and Tumor necrosis factor-binding protein 2
hide full assembly name
Multimeric state: hetero octamer
Accessible surface area: 51614.71 Å2
Buried surface area: 14317.12 Å2
Dissociation area: 622.7 Å2
Dissociation energy (ΔGdiss): 3.49 kcal/mol
Dissociation entropy (TΔSdiss): 7.57 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-148933

Macromolecules

TNF receptor-associated factor 2
Chains: A, B, C, D, E, F
Length: 192 amino acids
Theoretical weight: 21.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q12933 (Residues: 310-501; Coverage: 38%)
Gene names: TRAF2, TRAP3
Pfam:
InterPro:
CATH: Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A
SCOP:
TNF receptor-associated factor 2 in PDB entry 1ca9, assembly 1, front view.
TNF receptor-associated factor 2 in PDB entry 1ca9, assembly 1, side view.
TNF receptor-associated factor 2 in PDB entry 1ca9, assembly 1, top view.
Molecule details ›

Search similar proteins

Tumor necrosis factor-binding protein 2
Chains: G, H
Length: 10 amino acids
Theoretical weight: 1.12 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P20333 (Residues: 420-428; Coverage: 2%)
Gene names: TNFBR, TNFR2, TNFRSF1B
Tumor necrosis factor-binding protein 2 in PDB entry 1ca9, assembly 1, front view.
Tumor necrosis factor-binding protein 2 in PDB entry 1ca9, assembly 1, side view.
Tumor necrosis factor-binding protein 2 in PDB entry 1ca9, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links