› 1cbq

X-ray diffraction
2.2Å resolution

CRYSTAL STRUCTURE OF CELLULAR RETINOIC-ACID-BINDING PROTEINS I AND II IN COMPLEX WITH ALL-TRANS-RETINOIC ACID AND A SYNTHETIC RETINOID

Released:
DOI: 10.2210/pdb1cbq/pdb
PDB entry 1cbq coloured by chain, front view.
PDB entry 1cbq coloured by chain, side view.
PDB entry 1cbq coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structures of cellular retinoic acid binding proteins I and II in complex with all-trans-retinoic acid and a synthetic retinoid.
Kleywegt GJ, Bergfors T, Senn H, Le Motte P, Gsell B, Shudo K, Jones TA
Structure 2 1241-58 (1994)
PMID: 7704533

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151432 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cellular retinoic acid-binding protein 2 Chain: A
Molecule details ›
Chain: A
Length: 137 amino acids
Theoretical weight: 15.58 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P29373 (Residues: 2-138; Coverage: 99%)
Gene name: CRABP2
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

2 bound ligands:
Ligand PO4 1 x PO4
Ligand RE9 1 x RE9
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P213
Unit cell:
a: 81.04Å b: 81.04Å c: 81.04Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.21 0.264
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

23 review citations

Fold change in evolution of protein structures.
Grishin NV. (2001)
22 more

2 mentions without citation

Recognition of functional sites in protein structures.
Shulman-Peleg et al. (2004)
1 more