Function and Biology Details
Reaction catalysed:
Similar to that of papain. As compared to cathepsin B, cathepsin L exhibits higher activity toward protein substrates, but has little activity on Z-Arg-Arg-NHMec, and no peptidyl-dipeptidase activity.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Procathepsin L (preferred)
PDBe Complex ID:
PDB-CPX-139718 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Procathepsin L
Molecule details ›
Chain: A
Length: 316 amino acids
Theoretical weight: 35.92 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
Sequence domains:
Structure domains: Cysteine proteinases
Length: 316 amino acids
Theoretical weight: 35.92 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
- Canonical:
P07711 (Residues: 18-333; Coverage: 100%)
Sequence domains:
Structure domains: Cysteine proteinases
