› 1d4u

Solution NMR

INTERACTIONS OF HUMAN NUCLEOTIDE EXCISION REPAIR PROTEIN XPA WITH RPA70 AND DNA: CHEMICAL SHIFT MAPPING AND 15N NMR RELAXATION STUDIES

Released:
DOI: 10.2210/pdb1d4u/pdb
PDB entry 1d4u coloured by chain, front view.
PDB entry 1d4u coloured by chain, side view.
PDB entry 1d4u coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Interactions of human nucleotide excision repair protein XPA with DNA and RPA70 Delta C327: chemical shift mapping and 15N NMR relaxation studies.
Buchko GW, Daughdrill GW, de Lorimier R, Rao B K, Isern NG, Lingbeck JM, Taylor JS, Wold MS, Gochin M, Spicer LD, Lowry DF, Kennedy MA
Biochemistry 38 15116-28 (1999)
PMID: 10563794

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149868 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA repair protein complementing XP-A cells Chain: A
Molecule details ›
Chain: A
Length: 111 amino acids
Theoretical weight: 13.28 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P23025 (Residues: 98-208; Coverage: 41%)
Gene names: XPA, XPAC
Sequence domains:
Structure domains: XPA C-terminal domain

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

9 review citations

Zinc and the gene.
Dreosti IE. (2001)
8 more

16 mentions without citation

XPA: A key scaffold for human nucleotide excision repair.
Sugitani et al. (2016)
15 more