Function and Biology Details
Biochemical function:
Biological process:
- not assigned
Cellular component:
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Alpha-1-antitrypsin (preferred)
PDBe Complex ID:
PDB-CPX-133785 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Alpha-1-antitrypsin
Molecule details ›
Chain: A
Length: 334 amino acids
Theoretical weight: 37.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:
Length: 334 amino acids
Theoretical weight: 37.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P01009 (Residues: 44-377; Coverage: 85%)
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:
Short peptide from AAT
Molecule details ›
Chain: B
Length: 41 amino acids
Theoretical weight: 4.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Structure domains: Serpins superfamily
Length: 41 amino acids
Theoretical weight: 4.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P01009 (Residues: 378-418; Coverage: 10%)
Structure domains: Serpins superfamily
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
RIGAKU RU200
Spacegroup:
P42212
Expression system: Escherichia coli
