EC 5.6.2.1: DNA topoisomerase
Reaction catalysed:
ATP-independent breakage of single-stranded DNA, followed by passage and rejoining
Systematic name:
DNA topoisomerase
Alternative Name(s):
- DNA topoisomerase I
- Nicking-closing enzyme
- Omega-protein
- Relaxing enzyme
- Swivelase
- Type I DNA topoisomerase
- Untwisting enzyme
GO terms
Biochemical function:
Biological process:
Cellular component:
Sequence families
Protein families (Pfam)
InterPro annotations
Structure domains
CATH domains
2.70.20.10
Class:
Mainly Beta
Architecture:
Distorted Sandwich
Topology:
Topoisomerase I; domain 3
Homology:
Topoisomerase I, domain 3
Occurring in:
1.10.460.10
Class:
Mainly Alpha
Architecture:
Orthogonal Bundle
Topology:
Topoisomerase I; domain 2
Homology:
Topoisomerase I, domain 2
Occurring in:
1.10.290.10
Class:
Mainly Alpha
Architecture:
Orthogonal Bundle
Topology:
Topoisomerase I; domain 4
Homology:
Topoisomerase I, domain 4
Occurring in: