Function and Biology Details
Reaction catalysed:
Geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Protein prenyltransferase, alpha subunit
- PFTB repeat
- Prenyltransferase subunit beta
- Geranylgeranyl transferase type-2 subunit beta
- Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid
- Leucine-rich repeat domain superfamily
- Rab geranylgeranyltransferase, alpha subunit, insert-domain
- Rab geranylgeranyltransferase, alpha subunit, insert-domain superfamily
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170665 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Geranylgeranyl transferase type-2 subunit alpha
Molecule details ›
Chains: A, C
Length: 567 amino acids
Theoretical weight: 65.01 KDa
Source organism: Rattus norvegicus
UniProt:
Sequence domains:
Length: 567 amino acids
Theoretical weight: 65.01 KDa
Source organism: Rattus norvegicus
UniProt:
- Canonical:
Q08602 (Residues: 1-567; Coverage: 100%)
Sequence domains:
- Protein prenyltransferase alpha subunit repeat
- Rab geranylgeranyl transferase alpha-subunit, insert domain
Geranylgeranyl transferase type-2 subunit beta
Molecule details ›
Chains: B, D
Length: 331 amino acids
Theoretical weight: 36.89 KDa
Source organism: Rattus norvegicus
UniProt:
Sequence domains: Prenyltransferase and squalene oxidase repeat
Structure domains: Glycosyltransferase
Length: 331 amino acids
Theoretical weight: 36.89 KDa
Source organism: Rattus norvegicus
UniProt:
- Canonical: Q08603 (Residues: 1-331; Coverage: 100%)
Sequence domains: Prenyltransferase and squalene oxidase repeat
Structure domains: Glycosyltransferase
