› 1dei

X-ray diffraction
1.6Å resolution

DESHEPTAPEPTIDE (B24-B30) INSULIN

Released:
DOI: 10.2210/pdb1dei/pdb
PDB entry 1dei coloured by chain, front view.
PDB entry 1dei coloured by chain, side view.
PDB entry 1dei coloured by chain, top view.
Source organism: Sus scrofa
Primary publication:
Crystal structure of desheptapeptide(B24-B30)insulin at 1.6 A resolution: implications for receptor binding.
Bao SJ, Xie DL, Zhang JP, Chang WR, Liang DC
Proc Natl Acad Sci U S A 94 2975-80 (1997)
PMID: 9096331

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-134237 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Insulin A chain Chains: A, C
Molecule details ›
Chains: A, C
Length: 21 amino acids
Theoretical weight: 2.38 KDa
Source organism: Sus scrofa
Expression system: Not provided
UniProt:
  • Canonical: P01315 (Residues: 88-108; Coverage: 25%)
Gene name: INS
Insulin B chain Chains: B, D
Molecule details ›
Chains: B, D
Length: 23 amino acids
Theoretical weight: 2.55 KDa
Source organism: Sus scrofa
Expression system: Not provided
UniProt:
  • Canonical: P01315 (Residues: 25-47; Coverage: 27%)
Gene name: INS

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P212121
Unit cell:
a: 57.4Å b: 56.3Å c: 23Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.196 0.215
Expression system: Not provided

Quick links

Citations

4 review citations

Growth factor receptors: structure, mechanism, and drug discovery.
McInnes et al. (1997)
3 more

2 mentions without citation

Crystal structure of desheptapeptide(B24-B30)insulin at 1.6 A resolution: implications for receptor binding.
Bao et al. (1997)
1 more