Function and Biology Details
Reaction catalysed:
Selective cleavage of Arg-|-Lys bond in complement factor B when in complex with complement subcomponent C3b or with cobra venom factor.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Complement factor D (preferred)
PDBe Complex ID:
PDB-CPX-133229 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Complement factor D
Molecule details ›
Chains: A, B
Length: 228 amino acids
Theoretical weight: 24.44 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
Length: 228 amino acids
Theoretical weight: 24.44 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P00746 (Residues: 26-253; Coverage: 98%)
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
