› 1dj6

X-ray diffraction
1Å resolution

COMPLEX OF A Z-DNA HEXAMER, D(CG)3, WITH SYNTHETIC POLYAMINE AT ROOM TEMPERATURE

Released:
DOI: 10.2210/pdb1dj6/pdb
PDB entry 1dj6 coloured by chain, front view.
PDB entry 1dj6 coloured by chain, side view.
PDB entry 1dj6 coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
The crystal structure of N(1)-[2-(2-amino-ethylamino)-ethyl]-ethane-1,2-diamine (polyamines) binding to the minor groove of d(CGCGCG)(2), hexamer at room temperature.
Ohishi H, Suzuki K, Ohtsuchi M, Hakoshima T, Rich A
FEBS Lett 523 29-34 (2002)
PMID: 12123799

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113682 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
5'-D(*CP*GP*CP*GP*CP*G)-3' Chains: A, B
Molecule details ›
Chains: A, B
Length: 6 nucleotides
Theoretical weight: 1.81 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:
Ligand MG 1 x MG
Ligand 104 2 x 104
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: OTHER
Spacegroup: P212121
Unit cell:
a: 17.93Å b: 31.36Å c: 44.62Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.169 0.14 0.169
Expression system: Not provided

Quick links

Citations

1 review citation

DNA-binding drugs caught in action: the latest 3D pictures of drug-DNA complexes.
Boer et al. (2009)
10 other articles

8 mentions without citation

DNA conformations and their sequence preferences.
Svozil et al. (2008)
7 more