› 1dpg

X-ray diffraction
2Å resolution

GLUCOSE 6-PHOSPHATE DEHYDROGENASE FROM LEUCONOSTOC MESENTEROIDES

Released:
DOI: 10.2210/pdb1dpg/pdb
PDB entry 1dpg coloured by chain, front view.
PDB entry 1dpg coloured by chain, side view.
PDB entry 1dpg coloured by chain, top view.
Source organism: Leuconostoc mesenteroides
Primary publication:
The three-dimensional structure of glucose 6-phosphate dehydrogenase from Leuconostoc mesenteroides refined at 2.0 A resolution.
Rowland P, Basak AK, Gover S, Levy HR, Adams MJ
Structure 2 1073-87 (1994)
PMID: 7881907

Function and Biology Details

Reaction catalysed: 
D-glucose 6-phosphate + NAD(P)(+) = 6-phospho-D-glucono-1,5-lactone + NAD(P)H
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145818 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glucose-6-phosphate 1-dehydrogenase Chains: A, B
Molecule details ›
Chains: A, B
Length: 485 amino acids
Theoretical weight: 54.39 KDa
Source organism: Leuconostoc mesenteroides
Expression system: Escherichia coli
UniProt:
  • Canonical: P11411 (Residues: 2-486; Coverage: 100%)
Gene name: zwf
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand PO4 3 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.5
Spacegroup: P3221
Unit cell:
a: 105.71Å b: 105.71Å c: 224.31Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.206 0.206 0.257
Expression system: Escherichia coli

Quick links

Citations

11 review citations

G6PD deficiency: the genotype-phenotype association.
Mason et al. (2007)
10 more

13 mentions without citation

The Blueprint of a Minimal Cell: MiniBacillus.
Reuß et al. (2016)
12 more