› 1dqv

X-ray diffraction
3.2Å resolution

CRYSTAL STRUCTURE OF SYNAPTOTAGMIN III C2A/C2B

Released:
DOI: 10.2210/pdb1dqv/pdb
PDB entry 1dqv coloured by chain, front view.
PDB entry 1dqv coloured by chain, side view.
PDB entry 1dqv coloured by chain, top view.
Source organism: Rattus rattus
Primary publication:
Crystal structure of the cytosolic C2A-C2B domains of synaptotagmin III. Implications for Ca(+2)-independent snare complex interaction.
Sutton RB, Ernst JA, Brunger AT
J Cell Biol 147 589-98 (1999)
PMID: 10545502

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-154178 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Synaptotagmin-3 Chain: A
Molecule details ›
Chain: A
Length: 296 amino acids
Theoretical weight: 33.25 KDa
Source organism: Rattus rattus
Expression system: Escherichia coli
UniProt:
  • Canonical: P40748 (Residues: 293-588; Coverage: 50%)
Gene name: Syt3
Sequence domains: C2 domain
Structure domains: C2 domain

Ligands and Environments

2 bound ligands:
Ligand MG 4 x MG
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL1-5
Spacegroup: P6222
Unit cell:
a: 125.959Å b: 125.959Å c: 118.438Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.293 0.293 0.348
Expression system: Escherichia coli

Quick links

Citations

31 review citations

SNARE-mediated membrane fusion.
Chen et al. (2001)
30 more

23 mentions without citation

Towards automated crystallographic structure refinement with phenix.refine.
Afonine et al. (2012)
22 more