› 1dtj

X-ray diffraction
2Å resolution

CRYSTAL STRUCTURE OF NOVA-2 KH3 K-HOMOLOGY RNA-BINDING DOMAIN

Released:
DOI: 10.2210/pdb1dtj/pdb
PDB entry 1dtj coloured by chain, front view.
PDB entry 1dtj coloured by chain, side view.
PDB entry 1dtj coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structures of Nova-1 and Nova-2 K-homology RNA-binding domains.
Lewis HA, Chen H, Edo C, Buckanovich RJ, Yang YY, Musunuru K, Zhong R, Darnell RB, Burley SK
Structure 7 191-203 (1999)
PMID: 10368286

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194020 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RNA-binding protein Nova-2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 76 amino acids
Theoretical weight: 8.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UNW9 (Residues: 406-480; Coverage: 15%)
Gene names: ANOVA, NOVA2, NOVA3
Sequence domains: KH domain
Structure domains: K Homology domain, type 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F2
Spacegroup: C2
Unit cell:
a: 66.5Å b: 61.1Å c: 97.3Å
α: 90° β: 98.2° γ: 90°
R-values:
R R work R free
0.236 0.225 0.279
Expression system: Escherichia coli

Quick links

Citations

15 review citations

The poly(C)-binding proteins: a multiplicity of functions and a search for mechanisms.
Makeyev et al. (2002)
14 more

13 mentions without citation

Crystal structure of the N-terminal domain of the secretin GspD from ETEC determined with the assistance of a nanobody.
Korotkov et al. (2009)
12 more