› 1dy2

X-ray diffraction
2Å resolution

Murine collagen alpha1(XV), endostatin domain

Released:
DOI: 10.2210/pdb1dy2/pdb
PDB entry 1dy2 coloured by chain, front view.
PDB entry 1dy2 coloured by chain, side view.
PDB entry 1dy2 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Endostatins derived from collagens XV and XVIII differ in structural and binding properties, tissue distribution and anti-angiogenic activity.
Sasaki T, Larsson H, Tisi D, Claesson-Welsh L, Hohenester E, Timpl R
J Mol Biol 301 1179-90 (2000)
PMID: 10966814

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-128655 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Restin Chain: A
Molecule details ›
Chain: A
Length: 180 amino acids
Theoretical weight: 20.09 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: O35206 (Residues: 1192-1367; Coverage: 13%)
Gene name: Col15a1
Sequence domains: Collagenase NC10 and Endostatin
Structure domains: Mannose-Binding Protein A, subunit A

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 33.55Å b: 57.7Å c: 71.67Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.2 0.249
Expression system: Homo sapiens

Quick links

Citations

55 review citations

Basement membranes: structure, assembly and role in tumour angiogenesis.
Kalluri R. (2003)
54 more