› 1dyl

Electron Microscopy
9Å resolution

9 ANGSTROM RESOLUTION CRYO-EM RECONSTRUCTION STRUCTURE OF SEMLIKI FOREST VIRUS (SFV) AND FITTING OF THE CAPSID PROTEIN STRUCTURE IN THE EM DENSITY

Released:
DOI: 10.2210/pdb1dyl/pdb
PDB entry 1dyl coloured by chain, front view.
PDB entry 1dyl coloured by chain, side view.
PDB entry 1dyl coloured by chain, top view.
Source organism: Semliki Forest virus
Primary publication:
Cryo-electron microscopy reveals the functional organization of an enveloped virus, Semliki Forest virus.
Mancini EJ, Clarke M, Gowen BE, Rutten T, Fuller SD
Mol Cell 5 255-66 (2000)
PMID: 10882067
Related structures: EMD-1015

Function and Biology Details

Reaction catalysed: 
Autocatalytic release of the core protein from the N-terminus of the togavirus structural polyprotein by hydrolysis of a -Trp-|-Ser- bond.
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo 240-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136785 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Capsid protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 149 amino acids
Theoretical weight: 16.25 KDa
Source organism: Semliki Forest virus
UniProt:
  • Canonical: P03315 (Residues: 119-267; Coverage: 12%)
Sequence domains: Alphavirus core protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 9Å
Relevant EMDB volumes: EMD-1015

Quick links

Citations

29 review citations

A structural perspective of the flavivirus life cycle.
Mukhopadhyay et al. (2005)
28 more

2 mentions without citation

Electron microscopy holdings of the Protein Data Bank: the impact of the resolution revolution, new validation tools, and implications for the future.
Burley et al. (2022)
1 more