› 1dz1

Solution NMR

Mouse HP1 (M31) C terminal (shadow chromo) domain

Released:
DOI: 10.2210/pdb1dz1/pdb
PDB entry 1dz1 coloured by chain, ensemble of 16 models, front view.
PDB entry 1dz1 coloured by chain, ensemble of 16 models, side view.
PDB entry 1dz1 coloured by chain, ensemble of 16 models, top view.
Source organism: Mus musculus
Primary publication:
The structure of mouse HP1 suggests a unique mode of single peptide recognition by the shadow chromo domain dimer.
Brasher SV, Smith BO, Fogh RH, Nietlispach D, Thiru A, Nielsen PR, Broadhurst RW, Ball LJ, Murzina NV, Laue ED
EMBO J 19 1587-97 (2000)
PMID: 10747027

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160775 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chromobox protein homolog 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 70 amino acids
Theoretical weight: 8.08 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P83917 (Residues: 104-171; Coverage: 37%)
Gene names: Cbx, Cbx1
Sequence domains: Chromo shadow domain
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

44 review citations

Heterochromatin revisited.
Grewal et al. (2007)
43 more

8 mentions without citation

Designing collagens to shed light on the multi-scale structure-function mapping of matrix disorders.
Gahlawat et al. (2024)
7 more