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CRYSTAL STRUCTURE OF METHYLMALONYL COA DECARBOXYLASE

Source organism: Escherichia coli
Biochemical function: carboxy-lyase activity
Biological process: fatty acid beta-oxidation
Cellular component: cytosol

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GO terms

Sequence family

Pfam Protein family (Pfam)
PF00378
Domain description: Enoyl-CoA hydratase/isomerase
Occurring in:
  1. Methylmalonyl-CoA decarboxylase
The deposited structure of PDB entry 1ef8 contains 3 copies of Pfam domain PF00378 (Enoyl-CoA hydratase/isomerase) in Methylmalonyl-CoA decarboxylase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR014748
Domain description: Enoyl-CoA hydratase, C-terminal
Occurring in:
  1. Methylmalonyl-CoA decarboxylase
IPR018376
Domain description: Enoyl-CoA hydratase/isomerase, conserved site
Occurring in:
  1. Methylmalonyl-CoA decarboxylase
IPR001753
Domain description: Enoyl-CoA hydratase/isomerase
Occurring in:
  1. Methylmalonyl-CoA decarboxylase
IPR029045
Domain description: ClpP/crotonase-like domain superfamily
Occurring in:
  1. Methylmalonyl-CoA decarboxylase

Structure domains

CATH CATH domains
1.10.12.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Lyase 2-enoyl-coa Hydratase; Chain A, domain 2
Homology: Lyase 2-enoyl-coa Hydratase, Chain A, domain 2
Occurring in:
  1. Methylmalonyl-CoA decarboxylase
The deposited structure of PDB entry 1ef8 contains 3 copies of CATH domain 1.10.12.10 (Lyase 2-enoyl-coa Hydratase; Chain A, domain 2) in Methylmalonyl-CoA decarboxylase. Showing 1 copy in chain A.
3.90.226.10
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: 2-enoyl-CoA Hydratase; Chain A, domain 1
Homology: 2-enoyl-CoA Hydratase; Chain A, domain 1
Occurring in:
  1. Methylmalonyl-CoA decarboxylase
The deposited structure of PDB entry 1ef8 contains 3 copies of CATH domain 3.90.226.10 (2-enoyl-CoA Hydratase; Chain A, domain 1) in Methylmalonyl-CoA decarboxylase. Showing 1 copy in chain A.
SCOP SCOP annotation
52103
Class: Alpha and beta proteins (a/b)
Fold: ClpP/crotonase
Superfamily: ClpP/crotonase
Occurring in:
  1. Methylmalonyl-CoA decarboxylase
The deposited structure of PDB entry 1ef8 contains 3 copies of SCOP domain 52103 (Crotonase-like) in Methylmalonyl-CoA decarboxylase. Showing 1 copy in chain A.

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