› 1elk

X-ray diffraction
1.5Å resolution

VHS domain of TOM1 protein from H. sapiens

Released:
DOI: 10.2210/pdb1elk/pdb
PDB entry 1elk coloured by chain, front view.
PDB entry 1elk coloured by chain, side view.
PDB entry 1elk coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of the VHS domain of human Tom1 (target of myb 1): insights into interactions with proteins and membranes.
Misra S, Beach BM, Hurley JH
Biochemistry 39 11282-90 (2000)
PMID: 10985773

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130088 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Target of Myb1 membrane trafficking protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 157 amino acids
Theoretical weight: 17.48 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O60784 (Residues: 1-153; Coverage: 31%)
Gene name: TOM1
Sequence domains: VHS domain
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X9B
Spacegroup: P21
Unit cell:
a: 42.07Å b: 52.86Å c: 73.22Å
α: 90° β: 99.75° γ: 90°
R-values:
R R work R free
0.201 0.193 0.221
Expression system: Escherichia coli

Quick links

Citations

13 review citations

The ESCRT complexes: structure and mechanism of a membrane-trafficking network.
Hurley et al. (2006)
12 more

13 mentions without citation

Overview of protein structural and functional folds.
Sun et al. (2004)
12 more