› 1enq

X-ray diffraction
2.5Å resolution

CO-CRYSTALS OF DEMETALLIZED CONCANAVALIN A WITH ZINC HAVING A ZINC ION BOUND IN THE S1 SITE

Released:
DOI: 10.2210/pdb1enq/pdb
PDB entry 1enq coloured by chain, front view.
PDB entry 1enq coloured by chain, side view.
PDB entry 1enq coloured by chain, top view.
Source organism: Canavalia ensiformis
Primary publication:
Sequential structural changes upon zinc and calcium binding to metal-free concanavalin A.
Bouckaert J, Poortmans F, Wyns L, Loris R
J Biol Chem 271 16144-50 (1996)
PMID: 8663112

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136271 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Concanavalin-A, 2nd part Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 237 amino acids
Theoretical weight: 25.62 KDa
Source organism: Canavalia ensiformis
UniProt:
  • Canonical: P02866 (Residues: 28-148; Coverage: 46%)
Sequence domains: Legume lectin domain
Structure domains: Jelly Rolls

Ligands and Environments

1 bound ligand:
Ligand ZN 4 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 67.23Å b: 113.03Å c: 122.14Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.198 0.284

Quick links

Citations

3 review citations

Proteins that bind high-mannose sugars of the HIV envelope.
Botos et al. (2005)
2 more

1 mention without citation

Predicting binding sites from unbound versus bound protein structures.
Clark et al. (2020)