Function and Biology Details
Reaction catalysed:
ATP + [receptor-protein] = ADP + [receptor-protein] phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146283 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Bone morphogenetic protein 2
Molecule details ›
Chains: A, C
Length: 116 amino acids
Theoretical weight: 13.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Transforming growth factor beta like domain
Structure domains: Cystine-knot cytokines
Length: 116 amino acids
Theoretical weight: 13.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P12643 (Residues: 283-396; Coverage: 31%)
Sequence domains: Transforming growth factor beta like domain
Structure domains: Cystine-knot cytokines
Bone morphogenetic protein receptor type-1A
Molecule details ›
Chains: B, D
Length: 89 amino acids
Theoretical weight: 9.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Activin types I and II receptor domain
Structure domains: CD59
Length: 89 amino acids
Theoretical weight: 9.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P36894 (Residues: 55-143; Coverage: 18%)
Sequence domains: Activin types I and II receptor domain
Structure domains: CD59
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
RIGAKU RU200
Spacegroup:
P65
Expression system: Escherichia coli
