1f0c

X-ray diffraction
2.26Å resolution

STRUCTURE OF THE VIRAL SERPIN CRMA

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-139577 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Serine proteinase inhibitor 2 Chain: A
Molecule details ›
Chain: A
Length: 305 amino acids
Theoretical weight: 34.02 KDa
Source organism: Cowpox virus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P07385 (Residues: 1-305; Coverage: 89%)
Gene names: CPXV207, OPG199, SPI-2
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:
Serine proteinase inhibitor 2 Chain: B
Molecule details ›
Chain: B
Length: 36 amino acids
Theoretical weight: 4.11 KDa
Source organism: Cowpox virus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P07385 (Residues: 306-341; Coverage: 11%)
Gene names: CPXV207, OPG199, SPI-2

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: P212121
Unit cell:
a: 49.203Å b: 92.455Å c: 100.454Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.228 0.228 0.272
Expression system: Escherichia coli BL21(DE3)