EC 2.7.8.7: Holo-[acyl-carrier-protein] synthase
Reaction catalysed:
CoA-(4'-phosphopantetheine) + an apo-[acyl-carrier-protein] = adenosine 3',5'-bisphosphate + an [acyl-carrier-protein]
Systematic name:
CoA-(4'-phosphopantetheine):apo-[acyl-carrier-protein] 4'-pantetheinephosphotransferase
Alternative Name(s):
- 4'-phosphopantetheinyl transferase
- ACPS
- AcpS
- Acyl carrier protein holoprotein (holo-ACP) synthetase
- Acyl carrier protein synthase
- Acyl carrier protein synthetase
- Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase
- CoA:apo-[acyl-carrier-protein] pantetheinephosphotransferase
- Coenzyme A:fatty acid synthetase apoenzyme 4'-phosphopantetheine transferase
- Holo-ACP synthase
- Holo-ACP synthetase
- Holosynthase
- L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
- P-pant transferase
- PPTase
Protein family (Pfam)![The deposited structure of PDB entry 1f7l contains 1 copy of Pfam domain PF01648 (4'-phosphopantetheinyl transferase superfamily) in Holo-[acyl-carrier-protein] synthase. Showing 1 copy in chain A.](https://www.ebi.ac.uk/pdbe/static/entry/1f7l_1_A_Pfam_PF01648_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>1f7l</span> contains 1 copy of Pfam domain <span class='highlight'>PF01648 (4'-phosphopantetheinyl transferase superfamily)</span> in <span class='highlight'>Holo-[acyl-carrier-protein] synthase</span>. Showing 1 copy in chain <span class='highlight'>A</span>.")
InterPro annotations
CATH domain![The deposited structure of PDB entry 1f7l contains 1 copy of CATH domain 3.90.470.20 (Ribosomal Protein L22; Chain A) in Holo-[acyl-carrier-protein] synthase. Showing 1 copy in chain A.](https://www.ebi.ac.uk/pdbe/static/entry/1f7l_1_A_CATH_3.90.470.20_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>1f7l</span> contains 1 copy of CATH domain <span class='highlight'>3.90.470.20 (Ribosomal Protein L22; Chain A)</span> in <span class='highlight'>Holo-[acyl-carrier-protein] synthase</span>. Showing 1 copy in chain <span class='highlight'>A</span>.")
SCOP annotation![The deposited structure of PDB entry 1f7l contains 1 copy of SCOP domain 64418 (Holo-(acyl carrier protein) synthase ACPS) in Holo-[acyl-carrier-protein] synthase. Showing 1 copy in chain A.](https://www.ebi.ac.uk/pdbe/static/entry/1f7l_1_A_SCOP_64418_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>1f7l</span> contains 1 copy of SCOP domain <span class='highlight'>64418 (Holo-(acyl carrier protein) synthase ACPS)</span> in <span class='highlight'>Holo-[acyl-carrier-protein] synthase</span>. Showing 1 copy in chain <span class='highlight'>A</span>.")