› 1f88

X-ray diffraction
2.8Å resolution

CRYSTAL STRUCTURE OF BOVINE RHODOPSIN

Released:
DOI: 10.2210/pdb1f88/pdb
PDB entry 1f88 coloured by chain, front view.
PDB entry 1f88 coloured by chain, side view.
PDB entry 1f88 coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Crystal structure of rhodopsin: A G protein-coupled receptor.
Palczewski K, Kumasaka T, Hori T, Behnke CA, Motoshima H, Fox BA, Le Trong I, Teller DC, Okada T, Stenkamp RE, Yamamoto M, Miyano M
Science 289 739-45 (2000)
PMID: 10926528

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136065 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Rhodopsin Chains: A, B
Molecule details ›
Chains: A, B
Length: 348 amino acids
Theoretical weight: 39.03 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P02699 (Residues: 1-348; Coverage: 100%)
Gene name: RHO
Sequence domains:
Structure domains: Rhodopsin 7-helix transmembrane proteins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, MAN
Carbohydrate polymer
3 bound ligands:
Ligand HG 6 x HG
Ligand ZN 4 x ZN
Ligand RET 2 x RET
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P41
Unit cell:
a: 97.246Å b: 97.246Å c: 149.544Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.186 0.186 0.238

Quick links

Citations

725 review citations

Seven-transmembrane receptors.
Pierce et al. (2002)
724 more

248 mentions without citation

International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors.
Fredholm et al. (2001)
247 more