› 1f97

X-ray diffraction
2.5Å resolution

SOLUBLE PART OF THE JUNCTION ADHESION MOLECULE FROM MOUSE

Released:
DOI: 10.2210/pdb1f97/pdb
PDB entry 1f97 coloured by chain, front view.
PDB entry 1f97 coloured by chain, side view.
PDB entry 1f97 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
X-ray structure of junctional adhesion molecule: structural basis for homophilic adhesion via a novel dimerization motif.
Kostrewa D, Brockhaus M, D'Arcy A, Dale GE, Nelboeck P, Schmid G, Mueller F, Bazzoni G, Dejana E, Bartfai T, Winkler FK, Hennig M
EMBO J 20 4391-8 (2001)
PMID: 11500366

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131583 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Junctional adhesion molecule A Chain: A
Molecule details ›
Chain: A
Length: 212 amino acids
Theoretical weight: 22.85 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: O88792 (Residues: 27-238; Coverage: 77%)
Gene names: F11r, Jam1, Jcam, Jcam1
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ELLIOTT GX-21
Spacegroup: I222
Unit cell:
a: 42.54Å b: 83.28Å c: 130.64Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.15 0.15 0.21
Expression system: Spodoptera frugiperda

Quick links

Citations

57 review citations

The tight junction: a multifunctional complex.
Schneeberger et al. (2004)
56 more

9 mentions without citation

Structural Features of Tight-Junction Proteins.
Heinemann et al. (2019)
8 more