› 1fc1

X-ray diffraction
2.9Å resolution

CRYSTALLOGRAPHIC REFINEMENT AND ATOMIC MODELS OF A HUMAN FC FRAGMENT AND ITS COMPLEX WITH FRAGMENT B OF PROTEIN A FROM STAPHYLOCOCCUS AUREUS AT 2.9-AND 2.8-ANGSTROMS RESOLUTION

Released:
DOI: 10.2210/pdb1fc1/pdb
PDB entry 1fc1 coloured by chain, front view.
PDB entry 1fc1 coloured by chain, side view.
PDB entry 1fc1 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A resolution.
Deisenhofer J
Biochemistry 20 2361-70 (1981)
PMID: 7236608

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134849 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Immunoglobulin heavy constant gamma 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 224 amino acids
Theoretical weight: 25.24 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P01857 (Residues: 106-328; Coverage: 56%)
Gene name: IGHG1
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, MAN, GAL, FUC
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 80.4Å b: 146.4Å c: 50.4Å
α: 90° β: 90° γ: 90°
Expression system: Not provided

Quick links

Citations

151 review citations

Fcgamma receptors as regulators of immune responses.
Nimmerjahn et al. (2008)
150 more

39 mentions without citation

The intrinsic and extrinsic effects of N-linked glycans on glycoproteostasis.
Hebert et al. (2014)
38 more