› 1fib

X-ray diffraction
2.1Å resolution

RECOMBINANT HUMAN GAMMA-FIBRINOGEN CARBOXYL TERMINAL FRAGMENT (RESIDUES 143-411) BOUND TO CALCIUM AT PH 6.0

Released:
DOI: 10.2210/pdb1fib/pdb
PDB entry 1fib coloured by chain, front view.
PDB entry 1fib coloured by chain, side view.
PDB entry 1fib coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of a 30 kDa C-terminal fragment from the gamma chain of human fibrinogen.
Yee VC, Pratt KP, Côté HC, Trong IL, Chung DW, Davie EW, Stenkamp RE, Teller DC
Structure 5 125-38 (1997)
PMID: 9016719

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136036 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fibrinogen gamma chain Chain: A
Molecule details ›
Chain: A
Length: 269 amino acids
Theoretical weight: 30.24 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P02679 (Residues: 169-433; Coverage: 62%)
Gene names: FGG, PRO2061
Sequence domains: Fibrinogen beta and gamma chains, C-terminal globular domain
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21
Unit cell:
a: 37.53Å b: 68.42Å c: 47.67Å
α: 90° β: 105.36° γ: 90°
R-values:
R R work R free
0.159 0.159 0.227
Expression system: Komagataella pastoris

Quick links

Citations

23 review citations

Fibrinogen and fibrin structure and functions.
Mosesson MW. (2005)
22 more

2 mentions without citation

Ligand recognition specificity of leukocyte integrin αMβ2 (Mac-1, CD11b/CD18) and its functional consequences.
Podolnikova et al. (2015)
1 more