› 1fnh

X-ray diffraction
2.8Å resolution

CRYSTAL STRUCTURE OF HEPARIN AND INTEGRIN BINDING SEGMENT OF HUMAN FIBRONECTIN

Released:
DOI: 10.2210/pdb1fnh/pdb
PDB entry 1fnh coloured by chain, front view.
PDB entry 1fnh coloured by chain, side view.
PDB entry 1fnh coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of a heparin- and integrin-binding segment of human fibronectin.
Sharma A, Askari JA, Humphries MJ, Jones EY, Stuart DI
EMBO J 18 1468-79 (1999)
PMID: 10075919

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136132 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ugl-Y3 Chain: A
Molecule details ›
Chain: A
Length: 271 amino acids
Theoretical weight: 29.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02751 (Residues: 1812-2082; Coverage: 11%)
Gene names: FN, FN1
Sequence domains: Fibronectin type III domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: I222
Unit cell:
a: 68.58Å b: 86.29Å c: 142.8Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.216 0.216 0.295
Expression system: Escherichia coli

Quick links

Citations

19 review citations

Assembly of fibronectin extracellular matrix.
Singh et al. (2010)
18 more

16 mentions without citation

Dynamic structure of plasma fibronectin.
Maurer et al. (2015)
15 more