› 1foh

X-ray diffraction
2.4Å resolution

Function and Biology Details

Reaction catalysed: 
Phenol + NADPH + O(2) = catechol + NADP(+) + H(2)O
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-147274 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phenol hydroxylase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 664 amino acids
Theoretical weight: 75.2 KDa
Source organism: Cutaneotrichosporon cutaneum
Expression system: Escherichia coli
UniProt:
  • Canonical: P15245 (Residues: 2-665; Coverage: 100%)
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand FAD 4 x FAD
1 bound ligand:
Ligand IPH 4 x IPH
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7B
Spacegroup: P21
Unit cell:
a: 100.03Å b: 150.68Å c: 114.92Å
α: 90° β: 114.68° γ: 90°
R-values:
R R work R free
0.217 0.217 0.278
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Flavoprotein monooxygenases, a diverse class of oxidative biocatalysts.
van Berkel et al. (2006)
5 more

18 mentions without citation

Structural biology of type VI secretion systems.
Cascales et al. (2012)
17 more