Function and Biology

TWO HUMAN C-FOS:C-JUN:DNA COMPLEXES

Source organism: Homo sapiens
Biochemical function: DNA-binding transcription factor activity
Biological process: regulation of DNA-templated transcription
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00170
Domain description: bZIP transcription factor
Occurring in:
  1. Protein c-Fos
  2. Transcription factor Jun
The deposited structure of PDB entry 1fos contains 2 copies of Pfam domain PF00170 (bZIP transcription factor) in Protein c-Fos. Showing 1 copy in chain E.
The deposited structure of PDB entry 1fos contains 2 copies of Pfam domain PF00170 (bZIP transcription factor) in Transcription factor Jun. Showing 1 copy in chain H.

InterPro InterPro annotations
IPR004827
Domain description: Basic-leucine zipper domain
Occurring in:
  1. Protein c-Fos
  2. Transcription factor Jun
IPR002112
Domain description: Transcription factor Jun
Occurring in:
  1. Transcription factor Jun
IPR000837
Domain description: AP-1 transcription factor
Occurring in:
  1. Protein c-Fos
IPR046347
Domain description: Basic-leucine zipper domain superfamily
Occurring in:
  1. Protein c-Fos
  2. Transcription factor Jun

Structure domain

CATH CATH domain
1.20.5.170
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homology: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Occurring in:
  1. Protein c-Fos
  2. Transcription factor Jun
The deposited structure of PDB entry 1fos contains 2 copies of CATH domain 1.20.5.170 (Single alpha-helices involved in coiled-coils or other helix-helix interfaces) in Protein c-Fos. Showing 1 copy in chain E.
The deposited structure of PDB entry 1fos contains 2 copies of CATH domain 1.20.5.170 (Single alpha-helices involved in coiled-coils or other helix-helix interfaces) in Transcription factor Jun. Showing 1 copy in chain H.
SCOP SCOP annotation
57960
Class: Coiled coil proteins
Fold: Parallel coiled-coil
Superfamily: Leucine zipper domain
Occurring in:
  1. Protein c-Fos
  2. Transcription factor Jun
The deposited structure of PDB entry 1fos contains 2 copies of SCOP domain 57960 (Leucine zipper domain) in Protein c-Fos. Showing 1 copy in chain E.
The deposited structure of PDB entry 1fos contains 2 copies of SCOP domain 57960 (Leucine zipper domain) in Transcription factor Jun. Showing 1 copy in chain H.