1g6v

X-ray diffraction
3.5Å resolution

Complex of the camelid heavy-chain antibody fragment CAB-CA05 with bovine carbonic anhydrase

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-224927 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Carbonic anhydrase 2 Chain: A
Molecule details ›
Chain: A
Length: 260 amino acids
Theoretical weight: 29.29 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00921 (Residues: 1-256; Coverage: 99%)
Gene name: CA2
Sequence domains: Eukaryotic-type carbonic anhydrase
Structure domains: Alpha carbonic anhydrase
ANTIBODY HEAVY CHAIN Chain: K
Molecule details ›
Chain: K
Length: 126 amino acids
Theoretical weight: 13.53 KDa
Source organism: Camelus dromedarius
Expression system: Escherichia coli
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7A
Spacegroup: P41212
Unit cell:
a: 83.86Å b: 83.86Å c: 224.05Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.21 0.276
Expression system: Escherichia coli