› 1gdh

X-ray diffraction
2.4Å resolution

CRYSTAL STRUCTURE OF A NAD-DEPENDENT D-GLYCERATE DEHYDROGENASE AT 2.4 ANGSTROMS RESOLUTION

Released:
DOI: 10.2210/pdb1gdh/pdb
PDB entry 1gdh coloured by chain, front view.
PDB entry 1gdh coloured by chain, side view.
PDB entry 1gdh coloured by chain, top view.
Source organism: Hyphomicrobium methylovorum
Primary publication:
Crystal structure of a NAD-dependent D-glycerate dehydrogenase at 2.4 A resolution.
Goldberg JD, Yoshida T, Brick P
J Mol Biol 236 1123-40 (1994)
PMID: 8120891

Function and Biology Details

Reaction catalysed: 
D-glycerate + NAD(+) = hydroxypyruvate + NADH
Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153160 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glycerate dehydrogenase Chains: A, B
Molecule details ›
Chains: A, B
Length: 320 amino acids
Theoretical weight: 34.93 KDa
Source organism: Hyphomicrobium methylovorum
Expression system: Not provided
UniProt:
  • Canonical: P36234 (Residues: 3-322; Coverage: 99%)
Sequence domains:
Structure domains: NAD(P)-binding Rossmann-like Domain

Ligands and Environments

1 bound ligand:
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P1
Unit cell:
a: 60.41Å b: 60.53Å c: 66.29Å
α: 102.3° β: 113.73° γ: 102.73°
R-values:
R R work R free
0.189 0.189 not available
Expression system: Not provided

Quick links

Citations

7 review citations

Evolution of rosmarinic acid biosynthesis.
Petersen et al. (2009)
6 more

5 mentions without citation

Structural genomics: a pipeline for providing structures for the biologist.
Chance et al. (2002)
4 more