› 1gfd

Solution NMR

SOLUTION STRUCTURE AND LIGAND-BINDING SITE OF THE C-TERMINAL SH3 DOMAIN OF GRB2

Released:
DOI: 10.2210/pdb1gfd/pdb
PDB entry 1gfd coloured by chain, ensemble of 20 models, front view.
PDB entry 1gfd coloured by chain, ensemble of 20 models, side view.
PDB entry 1gfd coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2.
Kohda D, Terasawa H, Ichikawa S, Ogura K, Hatanaka H, Mandiyan V, Ullrich A, Schlessinger J, Inagaki F
Structure 2 1029-40 (1994)
PMID: 7881903

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158852 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Growth factor receptor-bound protein 2 Chain: A
Molecule details ›
Chain: A
Length: 59 amino acids
Theoretical weight: 6.79 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P62993 (Residues: 159-215; Coverage: 26%)
Gene names: ASH, GRB2
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

8 review citations

Membrane-associated guanylate kinases regulate adhesion and plasticity at cell junctions.
Funke et al. (2005)
7 more

3 mentions without citation

BP-Dock: a flexible docking scheme for exploring protein-ligand interactions based on unbound structures.
Bolia et al. (2014)
2 more