› 1ggz

X-ray diffraction
1.5Å resolution

CRYSTAL STRUCTURE OF THE CALMODULIN-LIKE PROTEIN (HCLP) FROM HUMAN EPITHELIAL CELLS

Released:
DOI: 10.2210/pdb1ggz/pdb
PDB entry 1ggz coloured by chain, front view.
PDB entry 1ggz coloured by chain, side view.
PDB entry 1ggz coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of human calmodulin-like protein: insights into its functional role.
Han BG, Han M, Sui H, Yaswen P, Walian PJ, Jap BK
FEBS Lett 521 24-30 (2002)
PMID: 12067719

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151012 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calmodulin-like protein 3 Chain: A
Molecule details ›
Chain: A
Length: 148 amino acids
Theoretical weight: 16.78 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P27482 (Residues: 2-149; Coverage: 99%)
Gene name: CALML3
Sequence domains:
Structure domains: EF-hand

Ligands and Environments

1 bound ligand:
Ligand CA 4 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P21212
Unit cell:
a: 63.38Å b: 93.63Å c: 24.86Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.183 0.183 0.221
Expression system: Escherichia coli

Quick links

Citations

2 review citations

The Role of Calmodulin in Tumor Cell Migration, Invasiveness, and Metastasis.
Villalobo et al. (2020)
1 more

6 mentions without citation

The NMDA receptor NR1 C1 region bound to calmodulin: structural insights into functional differences between homologous domains.
Ataman et al. (2007)
5 more