› 1gjx

Solution NMR

Solution structure of the lipoyl domain of the chimeric dihydrolipoyl dehydrogenase P64K from Neisseria meningitidis

Released:
DOI: 10.2210/pdb1gjx/pdb
PDB entry 1gjx coloured by chain, ensemble of 18 models, front view.
PDB entry 1gjx coloured by chain, ensemble of 18 models, side view.
PDB entry 1gjx coloured by chain, ensemble of 18 models, top view.
Source organism: Neisseria meningitidis
Primary publication:
Solution structure of the lipoyl domain of the chimeric dihydrolipoyl dehydrogenase P64K from Neisseria meningitidis.
Tozawa K, Broadhurst RW, Raine AR, Fuller C, Alvarez A, Guillen G, Padron G, Perham RN
Eur J Biochem 268 4908-17 (2001)
PMID: 11559360

Function and Biology Details

Reaction catalysed: 
Protein N(6)-(dihydrolipoyl)lysine + NAD(+) = protein N(6)-(lipoyl)lysine + NADH
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191699 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dihydrolipoyl dehydrogenase Chain: A
Molecule details ›
Chain: A
Length: 81 amino acids
Theoretical weight: 8.33 KDa
Source organism: Neisseria meningitidis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9JZ09 (Residues: 2-82; Coverage: 14%)
Gene names: NMB1344, lpdA2
Sequence domains: Biotin-requiring enzyme
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

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Citations

1 review citation

Nuclear magnetic resonance approaches in the study of 2-oxo acid dehydrogenase multienzyme complexes--a literature review.
Kumaran et al. (2013)
3 other articles