› 1gp3

X-ray diffraction
1.95Å resolution

Human IGF2R domain 11

Released:
DOI: 10.2210/pdb1gp3/pdb
PDB entry 1gp3 coloured by chain, front view.
PDB entry 1gp3 coloured by chain, side view.
PDB entry 1gp3 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of a functional IGF2R fragment determined from the anomalous scattering of sulfur.
Brown J, Esnouf RM, Jones MA, Linnell J, Harlos K, Hassan AB, Jones EY
EMBO J 21 1054-62 (2002)
PMID: 11867533

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145907 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cation-independent mannose-6-phosphate receptor Chain: A
Molecule details ›
Chain: A
Length: 143 amino acids
Theoretical weight: 15.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P11717 (Residues: 1508-1650; Coverage: 6%)
Gene names: IGF2R, MPRI
Sequence domains: Cation-independent mannose-6-phosphate receptor repeat
Structure domains: Mannose-6-phosphate receptor binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P212121
Unit cell:
a: 31.373Å b: 49.843Å c: 83.03Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.206 0.206 0.255
Expression system: Escherichia coli

Quick links

Citations

13 review citations

Mannose 6-phosphate receptors: new twists in the tale.
Ghosh et al. (2003)
12 more

1 mention without citation

Structure of a functional IGF2R fragment determined from the anomalous scattering of sulfur.
Brown et al. (2002)