› 1gqb

X-ray diffraction
1.8Å resolution

HUMAN MIR-RECEPTOR, REPEAT 11

Released:
DOI: 10.2210/pdb1gqb/pdb
PDB entry 1gqb coloured by chain, front view.
PDB entry 1gqb coloured by chain, side view.
PDB entry 1gqb coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Locating the anomalous scatterer substructures in halide and sulfur phasing.
Usón I, Schmidt B, von Bülow R, Grimme S, von Figura K, Dauter M, Rajashankar KR, Dauter Z, Sheldrick GM
Acta Crystallogr D Biol Crystallogr 59 57-66 (2003)
PMID: 12499540

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145907 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cation-independent mannose-6-phosphate receptor Chains: A, B
Molecule details ›
Chains: A, B
Length: 143 amino acids
Theoretical weight: 15.56 KDa
Source organism: Homo sapiens
Expression system: Cricetinae gen. sp.
UniProt:
  • Canonical: P11717 (Residues: 1508-1650; Coverage: 6%)
Gene names: IGF2R, MPRI
Sequence domains: Cation-independent mannose-6-phosphate receptor repeat
Structure domains: Mannose-6-phosphate receptor binding domain

Ligands and Environments

1 bound ligand:
Ligand BR 10 x BR
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X9B
Spacegroup: C2
Unit cell:
a: 102.426Å b: 49.06Å c: 74.38Å
α: 90° β: 129.01° γ: 90°
R-values:
R R work R free
0.209 not available 0.253
Expression system: Cricetinae gen. sp.

Quick links

Citations

4 review citations

The insulin-like growth factor-II/mannose-6-phosphate receptor: structure, distribution and function in the central nervous system.
Hawkes et al. (2004)
3 more