› 1gsc

X-ray diffraction
2.5Å resolution

NEW CRYSTAL FORMS OF A MU CLASS GLUTATHIONE S-TRANSFERASE FROM RAT LIVER

Released:
DOI: 10.2210/pdb1gsc/pdb
PDB entry 1gsc coloured by chain, front view.
PDB entry 1gsc coloured by chain, side view.
PDB entry 1gsc coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
New crystal forms of a micro-class glutathione S-transferase from rat liver.
Fu JH, Rose J, Tam MF, Wang BC
Acta Crystallogr D Biol Crystallogr 50 219-24 (1994)
PMID: 15299462

Function and Biology Details

Reaction catalysed: 
RX + glutathione = HX + R-S-glutathione
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138255 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione S-transferase Mu 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 217 amino acids
Theoretical weight: 25.82 KDa
Source organism: Rattus norvegicus
Expression system: Not provided
UniProt:
  • Canonical: P04905 (Residues: 2-218; Coverage: 100%)
Gene name: Gstm1
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21
Unit cell:
a: 97.377Å b: 81.109Å c: 69.425Å
α: 90° β: 109.16° γ: 90°
Expression system: Not provided

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Citations

2 review citations

Modeling the active sites of cytochrome P450s and glutathione S-transferases, two of the most important biotransformation enzymes.
De Groot et al. (1997)
1 more