› 1gsl

X-ray diffraction
2Å resolution

LECTIN (FOURTH ISOLATED FROM (GRIFFONIA SIMPLICIFOLIA)) COMPLEX WITH Y HUMAN BLOOD GROUP DETERMINANT

Released:
DOI: 10.2210/pdb1gsl/pdb
PDB entry 1gsl coloured by chain, front view.
PDB entry 1gsl coloured by chain, side view.
PDB entry 1gsl coloured by chain, top view.
Source organism: Griffonia simplicifolia
Primary publication:
Structures of the lectin IV of Griffonia simplicifolia and its complex with the Lewis b human blood group determinant at 2.0 A resolution.
Delbaere LT, Vandonselaar M, Prasad L, Quail JW, Wilson KS, Dauter Z
J Mol Biol 230 950-65 (1993)
PMID: 8478943

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150161 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Lectin-4 Chain: A
Molecule details ›
Chain: A
Length: 243 amino acids
Theoretical weight: 26.82 KDa
Source organism: Griffonia simplicifolia
UniProt:
  • Canonical: P24146 (Residues: 1-243; Coverage: 100%)
Sequence domains: Legume lectin domain
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: MAG, GAL, FUC
Carbohydrate polymer
Carbohydrate polymer : NEW Components: FUC, NAG, BMA
Carbohydrate polymer
2 bound ligands:
Ligand MN 1 x MN
Ligand CA 1 x CA
1 modified residue:
Ligand PCA 1 x PCA

Experiments and Validation Details

Entry percentile scores
Spacegroup: P42212
Unit cell:
a: 78.9Å b: 78.9Å c: 89.1Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.185 0.185 0.242

Quick links

Citations

6 review citations

Lectins.
Vijayan et al. (1999)
5 more

7 mentions without citation

Insights into the quaternary association of proteins through structure graphs: a case study of lectins.
Brinda et al. (2005)
6 more