1gxr

X-ray diffraction
1.65Å resolution

WD40 Region of Human Groucho/TLE1

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-170058 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transducin-like enhancer protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 337 amino acids
Theoretical weight: 36.85 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q04724 (Residues: 436-770; Coverage: 44%)
Gene name: TLE1
Sequence domains: WD domain, G-beta repeat
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P21
Unit cell:
a: 62.407Å b: 56.656Å c: 102.034Å
α: 90° β: 102.29° γ: 90°
R-values:
R R work R free
0.229 0.229 0.256
Expression system: Spodoptera frugiperda