Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138118 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Cellular tumor antigen p53
Molecule details ›
Chain: A
Length: 198 amino acids
Theoretical weight: 22.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: P53 DNA-binding domain
Structure domains: Immunoglobulin-like
Length: 198 amino acids
Theoretical weight: 22.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P04637 (Residues: 95-292; Coverage: 50%)
Sequence domains: P53 DNA-binding domain
Structure domains: Immunoglobulin-like
TP53-binding protein 1
Molecule details ›
Chains: B, D
Length: 249 amino acids
Theoretical weight: 28.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: BRCA1 C Terminus (BRCT) domain
Structure domains: BRCT domain
Length: 249 amino acids
Theoretical weight: 28.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q12888 (Residues: 1724-1972; Coverage: 13%)
Sequence domains: BRCA1 C Terminus (BRCT) domain
Structure domains: BRCT domain
Cellular tumor antigen p53
Molecule details ›
Chain: C
Length: 198 amino acids
Theoretical weight: 22.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: P53 DNA-binding domain
Structure domains: Immunoglobulin-like
Length: 198 amino acids
Theoretical weight: 22.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P04637 (Residues: 95-292; Coverage: 50%)
Sequence domains: P53 DNA-binding domain
Structure domains: Immunoglobulin-like
