› 1h04

X-ray diffraction
2Å resolution

Human CD55 domains 3 & 4

Released:
DOI: 10.2210/pdb1h04/pdb
PDB entry 1h04 coloured by chain, front view.
PDB entry 1h04 coloured by chain, side view.
PDB entry 1h04 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Mapping CD55 function. The structure of two pathogen-binding domains at 1.7 A.
Williams P, Chaudhry Y, Goodfellow IG, Billington J, Powell R, Spiller OB, Evans DJ, Lea S
J Biol Chem 278 10691-6 (2003)
PMID: 12499389

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139968 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Complement decay-accelerating factor Chain: P
Molecule details ›
Chain: P
Length: 125 amino acids
Theoretical weight: 13.31 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P08174 (Residues: 161-285; Coverage: 36%)
Gene names: CD55, CR, DAF
Sequence domains: Sushi repeat (SCR repeat)
Structure domains: Complement Module, domain 1

Ligands and Environments

1 bound ligand:
Ligand NI 1 x NI
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.6
Spacegroup: C2
Unit cell:
a: 125.7Å b: 20.4Å c: 52.7Å
α: 90° β: 111.5° γ: 90°
R-values:
R R work R free
0.214 0.214 0.259
Expression system: Komagataella pastoris

Quick links

Citations

7 review citations

Pathogenesis of Afa/Dr diffusely adhering Escherichia coli.
Servin AL. (2005)
6 more

2 mentions without citation

Network medicine approaches for identification of novel prognostic systems biomarkers and drug candidates for papillary thyroid carcinoma.
Kori et al. (2023)
1 more