› 1h2i

X-ray diffraction
2.7Å resolution

Human Rad52 protein, N-terminal domain

Released:
DOI: 10.2210/pdb1h2i/pdb
PDB entry 1h2i coloured by chain, front view.
PDB entry 1h2i coloured by chain, side view.
PDB entry 1h2i coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of the single-strand annealing domain of human RAD52 protein.
Singleton MR, Wentzell LM, Liu Y, West SC, Wigley DB
Proc Natl Acad Sci U S A 99 13492-7 (2002)
PMID: 12370410

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo undecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155038 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA repair protein RAD52 homolog Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V
Length: 209 amino acids
Theoretical weight: 23.09 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P43351 (Residues: 1-209; Coverage: 50%)
Gene name: RAD52
Sequence domains: Rad52/22 family double-strand break repair protein
Structure domains: DNA repair protein Rad52/59/22

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P21
Unit cell:
a: 117.259Å b: 127.319Å c: 191.227Å
α: 90° β: 90.29° γ: 90°
R-values:
R R work R free
0.225 0.225 0.262
Expression system: Escherichia coli

Quick links

Citations

24 review citations

Mechanism of eukaryotic homologous recombination.
San Filippo et al. (2008)
23 more

12 mentions without citation

Mechanism of homologous recombination and implications for aging-related deletions in mitochondrial DNA.
Chen XJ. (2013)
11 more